The Friday Labs · Research

Forgotten Proteome Atlas

Thousands of human proteins have never been properly studied. We know they exist, but not what they do. This atlas uses AI to give each of these "dark" proteins a first, readable guess at its job, together with its predicted 3D shape.

5,501dark human proteins (Pharos Tdark)
601dark proteins mapped so far
5control proteins to validate the model

Latest proteins

See all proteins →
ProteinPredicted functionStatus
Zinc finger X-linked protein ZXDBZXDB · P98169A human nucleoplasmic transcriptional regulator that uses a tandem array of zinc-finger modules to anchor onto regulatory DNA and assemble coactivator complexes that enhance transcription.Dark
Uncharacterized protein ZSWIM9ZSWIM9 · Q86XI8A modular human scaffold that organizes protein assemblies controlling blood progenitor differentiation.Dark
Zinc finger and SCAN domain-containing protein 25ZSCAN25 · Q6NSZ9A nuclear transcriptional regulator that assembles oligomeric complexes via an N‑terminal oligomerization module, targets specific genomic sites through a C‑terminal array of zinc fingers, and recruits a repression cassette to silence nearby RNA polymerase II promoters and enhancers.Dark
Zinc finger and SCAN domain-containing protein 22ZSCAN22 · P10073A nuclear transcriptional regulator that uses an N-terminal oligomerization module to assemble higher-order regulatory complexes and a C-terminal array of zinc-finger motifs to anchor the assemblies to specific genomic sites.Dark
Zinc finger protein 438ZNF438 · Q7Z4V0A human nuclear transcriptional regulator that uses a tandem array of C2H2 zinc fingers to bind DNA and assemble multiprotein complexes that predominantly repress gene expression.Dark